Older sleep structure
There is a short-term awakening in the sleep of the elderly, and it is impossible to maintain continuous sleep;
Decreased sleep time and quality of sleep may indicate metabolic syndrome in the elderly;
According to the SDB&SHHS health study statistics, there is a decrease in the amplitude of the delta wave activity of less than 75 μv. For quantifying the activity of the delta wave, an attempt is made to measure using a Fourier transform or a zero-crossing technique.
Hypothesis of changing sleep structure during aging
1. Effects of neuroendocrine and other body fluids;
2. The effects of various neurotransmitters and neuromodulators;
â—Ž aging is accompanied by a series of changes in neuroendocrine, including growth hormone, gonadotropin, hypothalamic-pituitary-adrenal HPA axis decline, melatonin changes;
â—Ž endogenous cortisol spontaneously increased secretion, the purpose of activation of the HPA axis, while causing a decrease in the proportion of REM sleep time;
â—Ž directly stimulate the HPA axis by injecting corticotropin releasing hormone, and the elderly will have more sleep-related arousals;
â—Ž Loss of sleep can cause certain body fluids, and pro-inflammatory cells such as interleukin (IL-6), cortisol, and growth hormone are associated with a certain part of the sleep structure (REM, III, awakening).
These substances represent the in vivo environment that develops into insomnia;
â—Ž has always believed that diet control can delay aging by reducing oxidative stress;
â—Ž effects of secretion of neuropeptides from hypothalamic secretin;
â—Ž decreased adenosine binding affinity causes changes in receptor levels;
The circadian rhythm of aging
The sleep-wake rhythm tends to become scattered within 24 hours;
Difficulty in sleep transition (difficult to adapt to shifts);
Daytime sleep-wake rhythm amplitude flat (daytime sensation);
Leading to sleep (have got used to getting up early and staying up late);
Visual impairment, old people's phase shift and weakened photoreceptor (cataract, macular degeneration) cause sleep disorders;
Insomnia in the elderly and its related risk factors
Prevalence, morbidity and medical risk factors;
Medical and chronic diseases are the cause of poor sleep quality;
Psychosocial factors;
Psychological factors, widowhood, depression, and trauma;
Dependence on sleep sleeping pills for more than 6 years means that the dominant factor is likely to be depression, not a medical condition;
The incentives are diverse and require treatment, otherwise it can lead to harmful results;
Longitudinal studies have shown that poor sleep quality can cause intermittent depression.
Related common diseases
Sleep restless legs syndrome and periodic leg movements;
Sleep disordered breathing;
The mystery of snoring and lethargy in the elderly: daytime sleepiness must be skeptical, longitudinal studies show that sleepiness may indicate adverse consequences, including depression, death
Wind, myocardial infarction and dementia.
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age
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